Sligo Rovers play their first ever Scottish Challenge Cup game on Saturday as Falkirk visit The Showgrounds for a second round tie.
The match kicks off at 7:45pm with tickets available at turnstiles.
John Russell is a big doubt due to a hip problem and is one of four players set to miss the next league game with Finn Harps in two weeks. Craig Roddan, Michael Leahy and Raffaele Cretaro are the others.
Goalkeeper Michael Schlingermann is also doubtful with a neck injury.
Manager Gerard Lyttle said: “There are differing factors at play which is wanting to play your strongest team available and also mindful of the players we have and have not available for that Finn Harps game.
“We are going four weeks without a league game which is very difficult for everyone. We want to prepare for that game in the best way we can, we have to protect our players that our struggling and we also want to do well in this game so all of those will be considered.
“This game is important to keep us fresh, ticking over and give our training a consequence because when you’ve got four weeks of not having that game at the end of week, it becomes a problem.
“We want to win this game and build on that performance in Cork. It’s so frustrating we haven’t been able to do yet but we have to cope with it and to play a strong opposition in a Cup game is one positive.
“Make no mistake we are playing a good side. They haven’t had the results early in the season but from watching them and speaking to Queen of the South manager Gary Naysmith, they are just not firing yet and I think will be higher up that table in Scotland at the end of the season.
“Queen of the South beat them 4-1 in their recent meeting but when I looked back I think everything dropped for them on that occasion. They were clinical and punished Falkirk. We want to find that display that can see us do something similar and see if it can take us to the next round.”